Leptospirosis is a
zoonotic disease transmitted by the spirochete bacterium Leptospira spp. The bacteria is shed in the urine of an
infected host which can include mice, raccoons, skunks, deer, sheep, dogs and
even humans. The bacteria remains viable in the environment as long as it is
moist, so it is most prevalent in Florida during the wet summer months.
Dogs most commonly
come in contact with the bacteria by licking urine off the grass, or drinking
from puddles in the yard that have been contaminated with infected urine.
Clinical signs are jaundice (yellowing of the skin, eyes), bloody urine, fever,
lethargy, vomiting, inappetance, and kidney failure, and death. The incubation
period in dogs is 2-20 days. In humans the signs include lethargy, fever, severe
headache, chills, muscle aches, vomiting, diarrhea, and jaundice, and death.
The incubation period in humans is 4-14 days. People who are exposed to
contaminated water such as surfers, and professionals who are exposed to
contaminated urine such as veterinarians, and slaughterhouse workers are most
at risk.
Diagnosis is made
from blood samples and fresh urine in early infections.
Treatment if caught
early, is with antibiotics such as penicillin, and doxycycline. Penicillin is
given initially to control shedding of the bacteria in the urine, then
doxycycline is used to get rid of the carrier state. The key is prevention.
There are no vaccines available for humans, but there are effective vaccines
for dogs. The canine leptospirosis vaccine contains the 4 most common serovars,
and is included in most distemper/parvo vaccine combination protocols. There
are many veterinary practices that do not include leptospirosis vaccine in
their annual vaccination protocol and 3 years ago we had 4 cases of
leptospirosis. Two of the dogs were not current on any vaccines, and the other
two came from veterinary hospitals that did not include leptospirosis in their
vaccine protocol. We were able to save two of the dogs. This also posed a
significant risk to the owners’ health. We advised them to avoid contact with
their dogs’ urine and confine the area where their dogs urinate to limit the
area that could become contaminated. This past month we had 2 young dogs with
unexplained kidney disease that were had not been vaccinated against
leptospirosis by their previous vets and their owners spent some anxious
moments while we waited for the leptospirosis titers to come in.
We strongly
recommend that all dogs be vaccinated against leptospirosis annually to prevent
this potentially fatal disease.